By Costas Ioannides
This definitive reference paintings describes intimately the enzyme platforms that perform the metabolism of xenobiotics, relatively medications. every one bankruptcy specializes in a selected enzyme method, emphasising its position within the activation and detoxication of chemical compounds. facets mentioned significantly contain: enzyme functionality within the metabolism and bioactivation of xenobiotics substrate specificity tissue distribution species distribution (to comprise laboratory animals and people) hormonal legislation intercourse ameliorations modulation by way of past publicity to different chemical substances age-dependent expression pharmacogenetics and modulation through illness. Enzyme platforms that Metabolise medicines and different Xenobiotics might be crucial examining for commercial study scientists operating within the fantastic chemical substances and pharmaceutical industries, in particular these enthusiastic about the security review of chemical compounds, and investigating their metabolism, pharmacokinetic features and toxicological homes. the character and scope of the booklet also will make it appealing to the study toxicologist and to postgraduate scholars learning toxicology, in addition to to clinicians and pharmacists.