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By Keith J. Dorrington, Michel H. Klein (auth.), Andor Szentivanyi M.D., Paul H. Maurer Ph.D., Bernard W. Janicki Ph.D. (eds.)

This e-book is predicated on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their constitution, synthesis, functionality, and scientific applicability in ailment. association of this symposium by means of the college of South Florida collage of medication was once triggered by way of the unprecedented present growth of knowledge on those subject matters typically, and within the box of antibody diver­ sity, particularly. the problems that encompass the final named size of this box, started to floor within the past due 1950's with the 1st conclusive genetic reviews having been replied, and a brand new set of innovations has been de­ fined. As we see it from the fabric offered during this quantity, now new and diversified questions are being raised and responded by means of reports in growth, and it can be anticipated that there'll be different questions that would be with us for a significantly longer time. We think that the symposium introduced jointly many famous investi­ gators with assorted backgrounds and coaching stories comparable to immunolo­ gists, microbiologists, biochemists, molecular biologists, and medical sci­ entists, therefore offering a good instance of the interdisciplinary worth of recent immunology and glossy biomedical technological know-how usually. We think, for this reason, that bringing those complicated subject matters to a large viewers of bio­ clinical scientists via this symposium in addition to this quantity is of price to the clinical and to the clinical community.

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130:289 (1984). E. A. Kabat and T. T. Wu, Attempts to locate complementarity-determining restdues in the variable positions of light and heavy chains of itmnuneglobulins, in: "Immunoglobulins," S. Kochwa and H. G. , Ann. Y. Acad. Sci. 190:382 (1971). E. A. Kabat, T~ Wu, H. Bilofsky, M. Reid-Miller, and H. Perry, "Sequences of Proteins of Itmnunological Interest. bulation and Analysis of Amino Acid and Nucleic Acid Sequences of Precursors, V-regions, C-regions, J-chain, S2-microglobulins, Major Histocompatibility Antigens, Thy-2, Complement, C-reactive Protein, Thymopoietin, Post-gatmna Globulin, and a,,-macroglobulin," U.

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